Lake Nipmuc Park was a popular resort in the early 20th century, featuring leading musical and vaudeville talent. Vintage postcards from this resort are frequently for sale on eBay. The first Aerosmith gig took place at Nipmuc Regional High School (now Miscoe Hill Middle School) in this town on November 6, 1970. Mendon is home to two Boy Scout (BSA) troops, Troop 1 Mendon and Troop 44 Mendon.
Mendon has teamed up with neighboring town Upton to make the Mendon Upton Regional School District (MURSD), this district features 4 schools. In elementary school the two towns are split and each have equally nice schools. However, in middle school the classes merge into one and attend Miscoe hill middle school. Finally, in high school they attend Nipmuc regional high school which was recently named one of the top 500 schools in the United States.
In 1986 Congress created the Blackstone River Valley National Heritage Corridor, a national park. Mendon falls within this corridor.
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